Functional modularity of nuclear hormone receptors in a Caenorhabditis elegans metabolic gene regulatory network

@inproceedings{Arda2010FunctionalMO,
  title={Functional modularity of nuclear hormone receptors in a Caenorhabditis elegans metabolic gene regulatory network},
  author={H. Efsun Arda and Stefan Taubert and Lesley T MacNeil and Colin C Conine and Ben Tsuda and Marc R. Van Gilst and Reynaldo Sequerra and Lynn Doucette-Stamm and Keith R. Yamamoto and Albertha J M Walhout},
  booktitle={Molecular systems biology},
  year={2010}
}
Gene regulatory networks (GRNs) provide insights into the mechanisms of differential gene expression at a systems level. GRNs that relate to metazoan development have been studied extensively. However, little is still known about the design principles, organization and functionality of GRNs that control physiological processes such as metabolism, homeostasis and responses to environmental cues. In this study, we report the first experimentally mapped metazoan GRN of Caenorhabditis elegans… CONTINUE READING

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