Functional modifications of the coupling of solubilized dopamine D2 receptors to guanine-nucleotide-binding proteins.

Abstract

The molecular basis for the regulation of high-affinity agonist, [3H]N-n-propylnorapomorphine ([3H]NPA), binding to cholate-solubilized dopamine D2 receptors was characterized using cations, guanine nucleotides and sulfhydryl-modifying agents. [3H]NPA binding displayed an absolute requirement for divalent cations in the solubilized preparation. Removal of… (More)

Topics

Cite this paper

@article{Kazmi1992FunctionalMO, title={Functional modifications of the coupling of solubilized dopamine D2 receptors to guanine-nucleotide-binding proteins.}, author={Syed Mohammad Husnain Kazmi and Lalit K. Srivastava and Ram Kumar Mishra}, journal={Biological signals}, year={1992}, volume={1 4}, pages={194-207} }