Functional melanocytes derived from human pluripotent stem cells engraft into pluristratified epidermis.

@article{Nissan2011FunctionalMD,
  title={Functional melanocytes derived from human pluripotent stem cells engraft into pluristratified epidermis.},
  author={Xavier Nissan and Lionel Larrib{\`e}re and Manoubia Saidani and Ilse Hurbain and C{\'e}dric Delevoye and Jessica Feteira and Gilles Lema{\^i}tre and Marc Peschanski and Christine Baldeschi},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2011},
  volume={108 36},
  pages={14861-6}
}
Melanocytes are essential for skin homeostasis and protection, and their defects in humans lead to a wide array of diseases that are potentially extremely severe. To date, the analysis of molecular mechanisms and the function of human melanocytes have been limited because of the difficulties in accessing large numbers of cells with the specific phenotypes. This issue can now be addressed via a differentiation protocol that allows melanocytes to be obtained from pluripotent stem cell lines… CONTINUE READING
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