Functional mapping — how to map and study the genetic architecture of dynamic complex traits

@article{Wu2006FunctionalM,
  title={Functional mapping — how to map and study the genetic architecture of dynamic complex traits},
  author={R. Wu and M. Lin},
  journal={Nature Reviews Genetics},
  year={2006},
  volume={7},
  pages={229-237}
}
  • R. Wu, M. Lin
  • Published 2006
  • Biology, Medicine
  • Nature Reviews Genetics
  • The development of any organism is a complex dynamic process that is controlled by a network of genes as well as by environmental factors. Traditional mapping approaches for analysing phenotypic data measured at a single time point are too simple to reveal the genetic control of developmental processes. A general statistical mapping framework, called functional mapping, has been proposed to characterize, in a single step, the quantitative trait loci (QTLs) or nucleotides (QTNs) that underlie a… CONTINUE READING
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