Functional magnetic resonance imaging of human prefrontal cortex activation during a spatial working memory task.

@article{McCarthy1994FunctionalMR,
  title={Functional magnetic resonance imaging of human prefrontal cortex activation during a spatial working memory task.},
  author={Gregory McCarthy and A. M. Blamire and Aina Puce and Anna Christina Nobre and Gilles R. Bloch and Fahmeed Hyder and Patricia S. Goldman-Rakic and Robert G. Shulman},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1994},
  volume={91 18},
  pages={8690-4}
}
High-speed magnetic resonance (MR) imaging was used to detect activation in the human prefrontal cortex induced by a spatial working memory task modeled on those used to elucidate neuronal circuits in nonhuman primates. Subjects were required to judge whether the location occupied by the current stimulus had been occupied previously over a sequence of 14 or 15 stimuli presented in various locations. Control tasks were similar in all essential respects, except that the subject's task was to… CONTINUE READING
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