Functional magnetic resonance imaging during deep brain stimulation: a pilot study in four patients with Parkinson's disease.

@article{Jech2001FunctionalMR,
  title={Functional magnetic resonance imaging during deep brain stimulation: a pilot study in four patients with Parkinson's disease.},
  author={Robert Jech and Du{\vs}an Urgo{\vs}{\'i}k and Jaroslav Tintera and A Nebuzelsk{\'y} and J Krasensky and Roman Li{\vs}{\vc}{\'a}k and Jan Roth and Ev{\vz}en Rů{\vz}i{\vc}ka},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  year={2001},
  volume={16 6},
  pages={1126-32}
}
Functional magnetic resonance imaging (fMRI) was performed in patients with Parkinson's disease during deep brain stimulation of the subthalamic nucleus (three patients) and during deep brain stimulation of the ventral intermedius nucleus of the thalamus (one patient). All showed an increase in blood oxygenation level-dependent signal in the subcortical regions ipsilateral to the stimulated nucleus. This effect cannot be simply explained by a mechanism of depolarization blockade; rather, it is… CONTINUE READING

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