Functional level of rat liver tryptophan 2 , 3 - dioxygenase messenger RNA during superinduction of enzyme with actinomycin D ( cell - free protein
Abstract
Tryptophan 2,3-dioxygenase [EC 1.13.11.11; L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)] activity is induced by glucocorticoid hormones and superinduced by actinomycin D. Previous experiments had shown that hormonal induction of the enzyme activity is accompanied by parallel increases in tryptophan 2,3-dioxygenase mRNA level. In this study, we… (More)
Topics
- Tryptophan
- Dactinomycin
- Actinomycin
- Tyrosine
- Steroids
- Transaminases
- Experiment
- enzyme activity
- Oxygen
- Dioxygenases
- Elegant degradation
- RNA, Messenger
- Amino Acids
- Glucocorticoids
- tryptophan 2,3 dioxygenase activity
- Steroid hormone
- Synergy
- Tryptophanase
- RNA Synthesis Inhibition
- Reticulocytes
- RNA chemical synthesis
- Parallel computing
- Liver carcinoma
- Security controls
- Diploidy
