Functional interrelationship between two tandem E. coli ribosomal RNA promoters

@article{Glaser1983FunctionalIB,
  title={Functional interrelationship between two tandem E. coli ribosomal RNA promoters},
  author={G. Glaser and Paolo Sarmientos and Michael Cashel},
  journal={Nature},
  year={1983},
  volume={302},
  pages={74-76}
}
The Escherichia coli chromosome carries seven cistrons encoding ribosomal RNA sequences1–3. In all cases studied, in vitro4–7 and in vivo8–10, it has been established that transcription is initiated from two tandem promoters. The expression of the rRNA cistrons is regulated in response to growth rate as well as to aminoacyl tRNA availability11. In the present study, a plasmid (pPSl) carrying the promoter region of the rrnA cistron fused to the terminator region of rrnB10 has been used for in… CONTINUE READING