Functional interdependence and colocalization of endothelial nitric oxide synthase and heat shock protein 90 in cerebral arteries.

@article{Khurana2000FunctionalIA,
  title={Functional interdependence and colocalization of endothelial nitric oxide synthase and heat shock protein 90 in cerebral arteries.},
  author={Vini G. Khurana and Kristian Feterik and Margaret J Springett and Daihiko Eguchi and Vipin N Shah and Zvonimir S. Katu{\vs}i{\'c}},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2000},
  volume={20 11},
  pages={1563-70}
}
Heat shock protein 90 (HSP90), an essential component of several signal transduction systems, participates in the activation of endothelial nitric oxide synthase (eNOS) in cells. The objective of the current study was to determine if HSP90 and eNOS were functionally interdependent and colocalized in the cerebral circulation. The authors used isometric force recording, cyclic 3'5'-guanosine monophosphate (cGMP) radioimmunoassay (RIA), and immunogold electron microscopy (EM) to study canine… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

Heat shock protein 90 modulates endothelial nitric oxide synthase activity and vascular reactivity in the newborn piglet pulmonary circulation.

American journal of physiology. Lung cellular and molecular physiology • 2007
View 3 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…