Functional interaction between the HIV transactivator Tat and the transcriptional coactivator PC4 in T cells.

@article{Holloway2000FunctionalIB,
  title={Functional interaction between the HIV transactivator Tat and the transcriptional coactivator PC4 in T cells.},
  author={Adele F Holloway and Filomena Occhiodoro and Gerhard Mittler and Michael Meisterernst and M. Frances Shannon},
  journal={The Journal of biological chemistry},
  year={2000},
  volume={275 28},
  pages={21668-77}
}
The human immunodeficiency virus (HIV) transactivator Tat is a potent activator of transcription from the HIV long terminal repeat and is essential for efficient viral gene expression and replication. Tat has been shown to interact with components of the basal transcription machinery and transcriptional activators. Here we identify the cellular coactivator… CONTINUE READING