Functional imaging within individual pain fibres ex vivo with optical microscopy.


Here we introduce a simple experimental approach for studying afferent pain fibre physiology. We have developed a mouse en bloc dural-skull preparation for optical microfluorometric imaging to directly study the physiological functioning in selectively identified, individual nociceptive fibre free nerve endings. Functional optical imaging using widefield… (More)
DOI: 10.1016/j.jneumeth.2011.04.015


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