Functional imaging of sequence learning in Parkinson's disease.

  title={Functional imaging of sequence learning in Parkinson's disease.},
  author={M. Carbon and David Eidelberg},
  journal={Journal of the neurological sciences},
  volume={248 1-2},
Sequence learning, a cognitive task linked to cortico-striatal function, is impaired in Parkinson's disease (PD). We chose this task as a behavioral paradigm to study the functional architecture of PD in treated and untreated conditions. In our studies, participants were scanned with H(2)(15)O while performing a kinematically controlled motor sequence learning task and a matching motor baseline task. Experiments revealed that a specific sequence learning network predicts learning in normal… CONTINUE READING


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