Functional imaging of brain responses to pain. A review and meta-analysis (2000)

@article{Peyron2000FunctionalIO,
  title={Functional imaging of brain responses to pain. A review and meta-analysis (2000)},
  author={Roland Peyron and B. Laurent and Luis Garcia-Larrea},
  journal={Neurophysiologie Clinique/Clinical Neurophysiology},
  year={2000},
  volume={30},
  pages={263-288}
}
Brain responses to pain, assessed through positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) are reviewed. Functional activation of brain regions are thought to be reflected by increases in the regional cerebral blood flow (rCBF) in PET studies, and in the blood oxygen level dependent (BOLD) signal in fMRI. rCBF increases to noxious stimuli are almost constantly observed in second somatic (SII) and insular regions, and in the anterior cingulate cortex (ACC), and… CONTINUE READING
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