Functional imaging and pain: behavior, perception, and modulation.

  title={Functional imaging and pain: behavior, perception, and modulation.},
  author={Carlo A. Porro},
  journal={The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry},
  volume={9 5},
  • Carlo A. Porro
  • Published 2003 in
    The Neuroscientist : a review journal bringing…
Time-dependent increases of local metabolic or blood flow rates have been described in spinal cord and brain during acute and chronic pain states in experimental animals, in parallel with changes of different behavioral endpoints of pain and hyperalgesia. In healthy human volunteers, pain intensity-related hemodynamic changes have been identified in a widespread, bilateral brain system including parietal, insular, cingulate, and frontal cortical areas, as well as thalamus, amygdala, and… CONTINUE READING


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