Functional identification and reconstitution of an odorant receptor in single olfactory neurons.

@article{Touhara1999FunctionalIA,
  title={Functional identification and reconstitution of an odorant receptor in single olfactory neurons.},
  author={Kazushige Touhara and Showichi Sengoku and Koichiro Inaki and Akio Tsuboi and Junzo Hirono and Tomohiko Sato and H. Sakano and Takeshi Haga},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1999},
  volume={96 7},
  pages={4040-5}
}
The olfactory system is remarkable in its capacity to discriminate a wide range of odorants through a series of transduction events initiated in olfactory receptor neurons. Each olfactory neuron is expected to express only a single odorant receptor gene that belongs to the G protein coupled receptor family. The ligand-receptor interaction, however, has not been clearly characterized. This study demonstrates the functional identification of olfactory receptor(s) for specific odorant(s) from… CONTINUE READING
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