Functional gut disorders: from motility to sensitivity disorders. A review of current and investigational drugs for their management.

@article{Ponti1998FunctionalGD,
  title={Functional gut disorders: from motility to sensitivity disorders. A review of current and investigational drugs for their management.},
  author={Fabrizio De Ponti and Juan Ram{\'o}n Malagelada},
  journal={Pharmacology & therapeutics},
  year={1998},
  volume={80 1},
  pages={49-88}
}
Functional gut disorders include several clinical entities defined on the basis of symptom patterns (e.g., functional dyspepsia, irritable bowel syndrome, functional abdominal pain, functional abdominal bloating), for which there is no established pathophysiological mechanism. Because there is no well-defined pathophysiological target, treatment should be aimed at symptom improvement. Prokinetics and antispasmodics have been widely used in the treatment of functional gut disorders on the… CONTINUE READING

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