Functional graphene oxide as a plasmid-based Stat3 siRNA carrier inhibits mouse malignant melanoma growth in vivo.

@article{Yin2013FunctionalGO,
  title={Functional graphene oxide as a plasmid-based Stat3 siRNA carrier inhibits mouse malignant melanoma growth in vivo.},
  author={Di Yin and Yang Li and Hang Lin and Baofeng Guo and Yanwei Du and Xin Li and Huijie Jia and Xuejian Zhao and Jun Tang and Ling Zhang},
  journal={Nanotechnology},
  year={2013},
  volume={24 10},
  pages={
          105102
        }
}
Graphene oxide (GO) has attracted intensive interest in the biomedical field in recent years. We investigate whether the use of functional graphene oxide as an efficient delivery system for delivering specific molecular antitumor therapeutics in vivo could achieve a more excellent antitumor effect. Constitutive activation of signal transducer and activator of transcription 3 (Stat3) promotes survival in a wide spectrum of human cancers. In this paper, we study the in vivo behavior of graphene… CONTINUE READING
Highly Cited
This paper has 28 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 16 citations

References

Publications referenced by this paper.
Showing 1-10 of 43 references

Antitumor effects of Stat3-siRNA and endostatin combined therapies, delivered by attenuated Salmonella, on orthotopically implanted hepatocarcinoma

  • H Jia
  • Cancer Immunol. Immunother
  • 2012
2 Excerpts