Functional genomics: the coming of age for Tetrahymena thermophila.

@article{Turkewitz2002FunctionalGT,
  title={Functional genomics: the coming of age for Tetrahymena thermophila.},
  author={Aaron P. Turkewitz and Eduardo Orias and Geoffrey M. Kapler},
  journal={Trends in genetics : TIG},
  year={2002},
  volume={18 1},
  pages={35-40}
}
Over the past decade, researchers have manipulated the unique biology of Tetrahymena thermophila to generate a premier experimental organism for functional genomic analysis. A diverse array of DNA transformation methods have spearheaded in vivo strategies for discovering and dissecting universal eukaryotic processes, such as telomere addition and chromatin remodeling. Compartmentalization of this protist's genome into two functionally distinct nuclei - the silent 'germline' micronucleus and the… CONTINUE READING

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