Functional genetics in Apicomplexa: potentials and limits.

@article{Limenitakis2011FunctionalGI,
  title={Functional genetics in Apicomplexa: potentials and limits.},
  author={Julien Limenitakis and Dominique Soldati-Favre},
  journal={FEBS letters},
  year={2011},
  volume={585 11},
  pages={
          1579-88
        }
}
The Apicomplexans are obligate intracellular protozoan parasites and the causative agents of severe diseases in humans and animals. Although complete genome sequences are available since many years and for several parasites, they are replete with putative genes of unassigned function. Forward and reverse genetic approaches are limited only to a few Apicomplexans that can either be propagated in vitro or in a convenient animal model. This review will compare and contrast the most recent… CONTINUE READING
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