Functional foldamers that target bacterial membranes: The effect of charge, amphiphilicity and conformation.

Abstract

By varying the molecular charge, shape and amphiphilicity of a series of conformationally distinct diarylureas it is possible to control the levels of phospholipid membrane lysis using membranes composed of bacterial lipid extracts. From the data obtained, it appears as though the lysis activity observed is not due to charge, conformation or amphiphilicity… (More)
DOI: 10.1016/j.bmc.2016.07.017

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Cite this paper

@article{PatilSen2016FunctionalFT, title={Functional foldamers that target bacterial membranes: The effect of charge, amphiphilicity and conformation.}, author={Yogita Patil-Sen and Sarah Rachel Dennison and Timothy J. Snape}, journal={Bioorganic & medicinal chemistry}, year={2016}, volume={24 18}, pages={4241-4245} }