Functional expression of the organic cation/carnitine transporter 2 in rat astrocytes.

@article{Inazu2006FunctionalEO,
  title={Functional expression of the organic cation/carnitine transporter 2 in rat astrocytes.},
  author={Masato Inazu and Hiroshi Takeda and Katsuyuki Maehara and Kyoji Miyashita and Akio Tomoda and Teruhiko Matsumiya},
  journal={Journal of neurochemistry},
  year={2006},
  volume={97 2},
  pages={424-34}
}
In this study, we sought to identify the transporters that mediate the uptake of L-carnitine and acetyl-L-carnitine in cultured rat cortical astrocytes. L-[(3)H]carnitine and acetyl-L-[(3)H]carnitine uptake were both saturable, and mediated by a single Na(+)-dependent transport system. Uptake of both was inhibited by L-carnitine, D-carnitine, acetyl-L… CONTINUE READING