Functional expression of connexin30 and connexin31 in the polarized human airway epithelium.

@article{Wiszniewski2007FunctionalEO,
  title={Functional expression of connexin30 and connexin31 in the polarized human airway epithelium.},
  author={Ludovic Wiszniewski and Javier Ruiz Sanz and Isabelle Scerri and Elena Gasparotto and Tecla Dudez and Jean Silvain Lacroix and Susanne Suter and Sabina Gallati and Marc Chanson},
  journal={Differentiation; research in biological diversity},
  year={2007},
  volume={75 5},
  pages={
          382-92
        }
}
Gap junctions are documented in the human airway epithelium but the functional expression and molecular identity of their protein constituents (connexins, Cx) in the polarized epithelium is not known. To address this question, we documented the expression of a family of epithelial Cx (Cx26, Cx30, Cx30.3, Cx31, Cx31.1, Cx32, Cx37, Cx40, and Cx43) in primary human airway epithelial cells (AEC) grown on porous supports. Under submerged conditions, AEC formed a monolayer of airway cells whereas the… CONTINUE READING

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