Functional expression of a full-length cDNA coding for rat neural cell adhesion molecule L1 mediates homophilic intercellular adhesion and migration of cerebellar neurons.

@article{Miura1992FunctionalEO,
  title={Functional expression of a full-length cDNA coding for rat neural cell adhesion molecule L1 mediates homophilic intercellular adhesion and migration of cerebellar neurons.},
  author={Misa Miura and Hiroaki Asou and Masakatsu Kobayashi and Keiichi Uyemura},
  journal={The Journal of biological chemistry},
  year={1992},
  volume={267 15},
  pages={10752-8}
}
Neural cell adhesion molecule L1 is postulated to be involved in cell-cell interaction, neurite elongation, fasciculation of axons, cell migration, and myelination. To determine the function of L1 directly, we have transfected rat L1 cDNA into mouse fibroblast L cells. Stable transformants expressing L1 showed uniform surface expression of the molecule… CONTINUE READING