Functional expression of CD80 and CD86 allows immunogenicity of malignant B cells from non-Hodgkin's lymphomas.

Abstract

We analyzed the accessory function of malignant B cells from non-Hodgkin's lymphomas (NHLs). Among the 70 samples of malignant B cells included, four patterns of expression of the costimulatory molecules CD80 and CD86 were distinguished (+/+, +/-, -/+ and -/-). In two-thirds of the cases, CD80, CD86, or both were expressed. To investigate the relevance of… (More)

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@article{Chaperot1999FunctionalEO, title={Functional expression of CD80 and CD86 allows immunogenicity of malignant B cells from non-Hodgkin's lymphomas.}, author={Laurence Chaperot and Joel Plumas and Martin Jacob and Frederic W Bost and J P Molens and Jean Jacques Sotto and Jean Claude Bensa}, journal={Experimental hematology}, year={1999}, volume={27 3}, pages={479-88} }