Functional expression and regulation of drug transporters in monolayer- and sandwich-cultured mouse hepatocytes.


Primary hepatocyte cultures are now considered as convenient models for in vitro analyzing liver drug transport. However, if primary human and rat hepatocytes have been well-characterized with respect to drug transporter expression and regulation, much less is known for primary mouse hepatocytes. The present study was therefore designed to gain insights… (More)
DOI: 10.1016/j.ejps.2013.01.013


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