Functional expression and intracellular signaling of UTP-sensitive P2Y receptors in theca-interstitial cells

@inproceedings{VzquezCuevas2010FunctionalEA,
  title={Functional expression and intracellular signaling of UTP-sensitive P2Y receptors in theca-interstitial cells},
  author={F G V{\'a}zquez-Cuevas and Erika P Z{\'a}rate-D{\'i}az and Edith Garay and Rogelio O Arellano},
  booktitle={Reproductive biology and endocrinology : RB&E},
  year={2010}
}
BACKGROUND Purinergic receptors are expressed in the ovary of different species; their physiological roles remain to be elucidated. UTP-sensitive P2Y receptor activity may regulate cell proliferation. The aim of the present work was to study the functional expression of these receptors in theca/interstitial cells (TIC). METHODS TIC were isolated by centrifugation in a Percoll gradient. P2Y receptors and cellular markers in TIC were detected by RT-PCR and Western blot. Intracellular calcium… CONTINUE READING

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