Functional excitatory microcircuits in neonatal cortex connect thalamus and layer 4.

  title={Functional excitatory microcircuits in neonatal cortex connect thalamus and layer 4.},
  author={Cuiping Zhao and Joseph P-Y Kao and Patrick O. Kanold},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={29 49},
The functional connectivity of the cerebral cortex is shaped by experience during development, especially during a critical period early in life. In the prenatal and neonatal cortex, transient neuronal circuits are formed by a population of subplate neurons (SPNs). However, SPNs are absent in the adult cortex. While SPNs are crucial for normal development of the cerebral cortex and of thalamocortical synapses, little is known about how they are integrated in the developing thalamocortical… CONTINUE READING
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