Functional evidence for multiple purinoceptor subtypes in the rat medial vestibular nucleus.

@article{Chessell1997FunctionalEF,
  title={Functional evidence for multiple purinoceptor subtypes in the rat medial vestibular nucleus.},
  author={Iain Chessell and Anton D. Michel and Patrick P. A. Humphrey},
  journal={Neuroscience},
  year={1997},
  volume={77 3},
  pages={783-91}
}
Extracellular recording techniques were used in brain slices to characterize excitatory responses produced by purine nucleotides in the rat medial vestibular nucleus, an area where functional purinoceptors have not previously been described. In the continued presence of the adenosine antagonist 8-cyclopentyl-1,3-dipropylxanthine, which alone caused a small increase in the spontaneous firing rate, the P2 purinoceptor agonists alpha,beta-methyleneadenosine 5'-triphosphate (alphabeta meATP) and… CONTINUE READING