Functional evaluation of the role of inhibitor of apoptosis proteins in chronic lymphocytic leukemia.

OBJECTIVE The slow accumulation of malignant cells in chronic lymphocytic leukemia (CLL) suggests a defect in the induction of apoptosis in these cells. Previous studies have found sporadic alterations in the apoptotic apparatus in CLL cells, but a widespread defect has not been detected until now. A crucial checkpoint in the progression of apoptosis is the… CONTINUE READING



Citations per Year

269 Citations

Semantic Scholar estimates that this publication has 269 citations based on the available data.

See our FAQ for additional information.