Functional equivalence of metarhodopsin II and the Gt-activating form of photolyzed bovine rhodopsin.

Abstract

Absorption of a photon by the visual pigment rhodopsin leads to the formation of an activated conformational state, denoted rho*, which is capable of activating the visual G-protein, Gt. The bleaching of rhodopsin can be resolved into a series of spectrally distinct photointermediates. Previous studies suggest that the photointermediate metarhodopsin II… (More)

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