• Corpus ID: 135634118

Functional encapsulation of small particles : quantification and control of the morphology of the coating layers : quantification and control of the morphology of the coating layers

  title={Functional encapsulation of small particles : quantification and control of the morphology of the coating layers : quantification and control of the morphology of the coating layers},
  author={F. L. Laksmana},
In this chapter, an overview of the important aspects of the formulation and the process development of a functional encapsulated product is given. It is shown that there is a need of quantification methods that enable tight control of the coating morphology and therefore the coating performance. Three aspects are described that can merit better characterization, involving (i) the effect of small molecules on the coating properties, (ii) the coating structurerelated quality, i.e. thickness… 
Influence of liquid formulation and impact conditions on the coating of hydrophobic surfaces
This study deals with elementary mechanisms involved in droplet–particle collisions during wet coating operations. The study focuses on rebound and splashing phenomena which may occur during the
Application of encapsulated superabsorbent polymers in cementitious materials for stimulated autogenous healing
Superabsorbent polymers have shown potential for use in mortar and concrete as self-healing agents. The main drawback is, however, that these superabsorbent polymers also absorb mixing water during
Fenomeni sudara kapi u procesu oblaganja Wurster tehnologijom
Ovo se istraživanje bavi mehanizmima sudara između kapljica i krutih cestica tijekom oblaganja tableta u laboratorijskoj izvedbi uređaja za oblaga


Quantitative Image Analysis for Evaluating the Coating Thickness and Pore Distribution in Coated Small Particles
A characterization method for coating structure based on image analysis, which is particularly promising for the rational design of coated particles in the pharmaceutical industry, can be used as a fast and effective tool to predict coating functionality.
Polymer Blends Used for the Coating of Multiparticulates: Comparison of Aqueous and Organic Coating Techniques
The type of coating technique strongly affects the film microstructure and, therefore, the release mechanism and rate from pellets coated with polymer blends, resulting in higher degrees of polymer-polymer interpenetration and, thus, tougher and less permeable film coatings.
Encapsulation of water sensitive products: effectiveness and assessment of fluid bed dry coating
Today, there is a real interest in the use of products containing some living cells or some other fragile substances in many industries, agriculture, chemical, pharmaceutical and food, because of
ABSTRACT The fluid bed encapsulation process consists of spraying a coating solution into a fluidized bed of solid particles. After several cycles of wetting–drying, a continuous film is formed. This
Nonuniformity of particle coating on a size distribution of particles in a fluidized bed coater
Abstract The focus of the current work is to evaluate the effect that particle size has on the uniformity of coating received during a batch fluidized bed coating process. Batches of near-spherical
Characterization of coating systems
  • L. Felton
  • Materials Science, Medicine
    AAPS PharmSciTech
  • 2008
Experimental techniques to assess various properties of both free and applied films, including water vapor and oxygen permeability, as well as thermal, mechanical, and adhesive characteristics are described.
The effect of spray mode and chamber geometry of fluid-bed coating equipment and other parameters on an aqueous-based ethylcellulose coating
Abstract Propranolol HCl pellets were prepared in a rotor-granulator by layering the drug powder onto nonpareil seeds. They were then coated with Aquacoat® (an aqueous dispersion of ethylcellulose)
Effect of the spray-drying process on the properties of coated films in fluidized bed granular coaters
Influences of spray drying a coating liquid on the properties of coated films were investigated by using three types of fluidized bed coaters. The top spray method with a conventional fluidized bed
Coating and Drying in Spouted Bed: Influence of the Liquid-Particle Work of Adhesion
The aim of this work is to analyze the resulting process: coating or drying, and the respective fluid dynamic behavior, by bottom-spraying polymeric suspensions on a spouted bed of inert particles.
A novel approach in the assessment of polymeric film formation and film adhesion on different pharmaceutical solid substrates
It was shown that the designed magnet probe test provides reliable and reproducible results when used for measurement of film adhesion and bonding strength.