Functional domains of a geminivirus replication protein.

  title={Functional domains of a geminivirus replication protein.},
  author={Beverly M. Orozco and Ann Miller and Sharon B. Settlage and Linda Hanley-Bowdoin},
  journal={The Journal of biological chemistry},
  volume={272 15},
Tomato golden mosaic virus, a member of the geminivirus family, has a single-stranded DNA genome that is replicated and transcribed in infected plant cells through the concerted action of viral and host factors. One viral protein, AL1, contributes to both processes by binding to a directly repeated, double-stranded DNA sequence located in the overlapping (+) strand origin of replication and AL1 promoter. The AL1 protein, which occurs as a multimeric complex in solution, also catalyzes DNA… CONTINUE READING

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