Functional divergence of duplicated c-myc genes in a tetraploid fish, the common carp (Cyprinus carpio).

Abstract

The proto-oncogene c-myc is thought to be one of the most important genes in controlling cell proliferation. In a tetraploid fish, two c-myc genes (CAM1 and CAM2) were previously isolated from the common carp, Cyprinus carpio, and were shown to have different expression patterns in adult tissues. Here we found that CAM1 and CAM2 proteins had distinct… (More)

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