Functional divergence and horizontal transfer of type IV secretion systems.

@article{Frank2005FunctionalDA,
  title={Functional divergence and horizontal transfer of type IV secretion systems.},
  author={A Carolin Frank and Cecilia M Alsmark and Mikael Thollesson and Siv G. E. Andersson},
  journal={Molecular biology and evolution},
  year={2005},
  volume={22 5},
  pages={1325-36}
}
The type IV secretion system (TFSSs) is a multifunctional family of translocation pathways that mediate the transfer of DNA among bacteria and deliver DNA and proteins to eukaryotic cells during bacterial infections. Horizontal transmission has dominated the evolution of the TFSS, as demonstrated here by a lack of congruence between the tree topology inferred from components of the TFSS and the presumed bacterial species divergence pattern. A parsimony analysis suggests that conjugation… CONTINUE READING

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