Functional disturbances due to structural remodeling in the failing human heart.

Abstract

In severely hypertrophied hearts structural remodeling occurs continuously and finally leads to heart failure. The remodeling process involves all structural components of the cardiomyocyte and all protein families and it consists of cellular enlargement accompanied by degeneration in addition to the occurrence of fibrosis. Nuclei are increased in size but… (More)

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Cite this paper

@article{Hein2002FunctionalDD, title={Functional disturbances due to structural remodeling in the failing human heart.}, author={Stefan Hein and Albrecht Elsaesser and Sawa Kostin and Robert Zimmermann and Jutta Schaper}, journal={Archives des maladies du coeur et des vaisseaux}, year={2002}, volume={95 9}, pages={815-20} }