Functional distribution of three types of Na+ channel on soma and processes of dorsal horn neurones of rat spinal cord.

@article{Safronov1997FunctionalDO,
  title={Functional distribution of three types of Na+ channel on soma and processes of dorsal horn neurones of rat spinal cord.},
  author={Boris V. Safronov and Matthias Wolff and Werner Vogel},
  journal={The Journal of physiology},
  year={1997},
  volume={503 ( Pt 2)},
  pages={371-85}
}
1. Voltage-gated Na+ channels and their distribution were studied by the patch-clamp technique in intact dorsal horn neurones in slices of newborn rat spinal cord and in neurones isolated from the slice by slow withdrawal of the recording pipette. This new method of neurone isolation was further used to study the roles of soma and axon in generation of action potentials. 2. Tetrodotoxin (TTX)-sensitive Na+ currents in intact neurones consisted of three components. A fast component with an… CONTINUE READING
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