Functional dissociation of the prefrontal cortex and the hippocampus in timing behavior.

Using the peak procedure, rats with aspiration lesions to the medial prefrontal cortex (PFC) or the hippocampus were tested for the acquisition of timing behavior and temporal memory. After surgery, rats were 1st trained to discriminate a 40-s interval and then tested for temporal memory with gap trials. Results indicated that lesions to the medial PFC… CONTINUE READING