Functional dissection of NEAT1 using genome editing reveals substantial localization of the NEAT1_1 isoform outside paraspeckles.

Abstract

Large numbers of long noncoding RNAs have been discovered in recent years, but only a few have been characterized. NEAT1 (nuclear paraspeckle assembly transcript 1) is a mammalian long noncoding RNA that is important for the reproductive physiology of mice, cancer development, and the formation of subnuclear bodies termed paraspeckles. The two major… (More)
DOI: 10.1261/rna.059477.116

Topics

Cite this paper

@article{Li2017FunctionalDO, title={Functional dissection of NEAT1 using genome editing reveals substantial localization of the NEAT1_1 isoform outside paraspeckles.}, author={Ruohan Li and Alan R Harvey and Stuart I. Hodgetts and Archa H Fox}, journal={RNA}, year={2017}, volume={23 6}, pages={872-881} }