Functional disruption of stress modulatory circuits in a model of temporal lobe epilepsy

@article{Wulsin2018FunctionalDO,
  title={Functional disruption of stress modulatory circuits in a model of temporal lobe epilepsy},
  author={A. Wulsin and Ana Franco-Villanueva and Christian Romancheck and Rachel L. Morano and Brittany L Smith and B. Packard and S. Danzer and J. Herman},
  journal={PLoS ONE},
  year={2018},
  volume={13}
}
Clinical data suggest that the neuroendocrine stress response is chronically dysregulated in a subset of patients with temporal lobe epilepsy (TLE), potentially contributing to both disease progression and the development of psychiatric comorbidities such as anxiety and depression. Whether neuroendocrine dysregulation and psychiatric comorbidities reflect direct effects of epilepsy-related pathologies, or secondary effects of disease burden particular to humans with epilepsy (i.e. social… Expand
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