Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits

Abstract

Our knowledge of the functions of metazoan ribosomal proteins in ribosome synthesis remains fragmentary. Using siRNAs, we show that knockdown of 31 of the 32 ribosomal proteins of the human 40S subunit (ribosomal protein of the small subunit [RPS]) strongly affects pre-ribosomal RNA (rRNA) processing, which often correlates with nucleolar chromatin… (More)
DOI: 10.1083/jcb.201005117

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Cite this paper

@inproceedings{ODonohue2010FunctionalDO, title={Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits}, author={Marie-Françoise O’Donohue and Val{\'e}rie Choesmel and Marl{\`e}ne Faubladier and G. Fichant and Pierre-Emmanuel Gleizes}, booktitle={The Journal of cell biology}, year={2010} }