Functional coronary microvascular injury evident as increased permeability due to brief ischemia and reperfusion.

@article{Dauber1990FunctionalCM,
  title={Functional coronary microvascular injury evident as increased permeability due to brief ischemia and reperfusion.},
  author={I M Dauber and K M Vanbenthuysen and Ivan F. McMurtry and Gregory S. Wheeler and Edward Joseph Lesnefsky and Lawrence D. Horwitz and John V. Weil},
  journal={Circulation research},
  year={1990},
  volume={66 4},
  pages={986-98}
}
Although morphological studies suggest that coronary vascular injury is a result of prolonged ischemia and subsequent reperfusion, whether functional coronary microvascular injury develops during brief in vivo ischemia is unclear. In other organs, permeability is a sensitive indicator of functional vascular injury. Therefore, a new double-indicator method of assessing vascular protein permeability, a method that is both sensitive and specific for vascular injury, was used to investigate the… CONTINUE READING

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