Functional coordination of microtubule-based and actin-based motility in melanophores

  title={Functional coordination of microtubule-based and actin-based motility in melanophores},
  author={V. I. Rodionov and Andrew J Hope and Tatyana M Svitkina and Gary G. Borisy},
  journal={Current Biology},
The fish melanophore has been considered the exemplar of microtubule-based organelle transport. In this system, a radial array of uniformly polarized microtubules [1] provides a framework on which dynein-related and kinesin-related motors drive pigment granules toward the minus or plus ends, respectively [2-4]. Stimulation of minus-end motors accounts satisfactorily for aggregation of granules at the cell center. Rapid dispersion is clearly microtubule-dependent; however, the uniform… CONTINUE READING
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Bridgman PC: Particles move along actin filament bundles in nerve growth cones

  • LL Evans
  • Proc Natl Acad Sci USA
  • 1995
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Regulation of organelle transport: lessons from color change in fish

  • LH Haimo, CD Thaler
  • BioEssays
  • 1994

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