Functional cooperation of simian virus 40 promoter factor 1 and CCAAT/enhancer-binding protein beta and delta in lipopolysaccharide-induced gene activation of IL-10 in mouse macrophages.

Abstract

Previous studies have revealed that LPS can activate transcription of the IL-10 gene promoter through an SV40 promoter factor 1 (Sp1) binding site in mouse macrophage RAW264.7. In this study, we determined that, in addition to Sp1, C/EBPbeta and delta were also involved in LPS-induced gene expression of IL-10. By transient transfection with 5'-deletion… (More)

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@article{Liu2003FunctionalCO, title={Functional cooperation of simian virus 40 promoter factor 1 and CCAAT/enhancer-binding protein beta and delta in lipopolysaccharide-induced gene activation of IL-10 in mouse macrophages.}, author={Yi-Wen Liu and Hui-Ping Tseng and Lei-Chin Chen and Ben-Kuen Chen and Wen-Chang Chang}, journal={Journal of immunology}, year={2003}, volume={171 2}, pages={821-8} }