Functional consequences of genetic variation in primates on tyrosine hydroxylase (TH) expression in vitro.

@article{Warner2009FunctionalCO,
  title={Functional consequences of genetic variation in primates on tyrosine hydroxylase (TH) expression in vitro.},
  author={Lisa R. Warner and Courtney C. Babbitt and Alexander E Primus and Tonya F. Severson and Ralph Haygood and Gregory A. Wray},
  journal={Brain research},
  year={2009},
  volume={1288},
  pages={1-8}
}
Tyrosine hydroxylase, the rate-limiting enzyme in catecholamine synthesis, is known to contain naturally occurring genetic variation in it's promoter region that associates with a number of neuropsychological disorders. As such, examining non-coding regions is important for understanding tyrosine hydroxylase function in human health and disease. We examined approximately 2 kb upstream of the translation start site within humans and non-human primates to obtain a fine resolution map of… CONTINUE READING
6 Citations
36 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 36 references

Similar Papers

Loading similar papers…