Functional connectivity of the amygdala in early-childhood-onset depression.

Abstract

OBJECTIVE Adult major depressive disorder (MDD) is associated with reduced cortico-limbic functional connectivity thought to indicate decreased top-down control of emotion. However, it is unclear whether such connectivity alterations are also present in early-childhood-onset MDD. METHOD A total of 51 children 7 through 11 years of age who had been… (More)
DOI: 10.1016/j.jaac.2011.07.019

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