Functional connectivity in the cognitive control network and the default mode network in late-life depression.

@article{Alexopoulos2012FunctionalCI,
  title={Functional connectivity in the cognitive control network and the default mode network in late-life depression.},
  author={George S. Alexopoulos and Matthew J. Hoptman and Dora Kanellopoulos and Christopher F. Murphy and Kelvin O. Lim and Faith M Gunning},
  journal={Journal of affective disorders},
  year={2012},
  volume={139 1},
  pages={
          56-65
        }
}
BACKGROUND Abnormalities have been identified in the Cognitive Control Network (CCN) and the Default Mode Network (DMN) during episodes of late-life depression. This study examined whether functional connectivity at rest (FC) within these networks characterizes late-life depression and predicts antidepressant response. METHODS 26 non-demented, non-MCI older adults were studied. Of these, 16 had major depression and 10 had no psychopathology. Depressed patients were treated with escitalopram… CONTINUE READING
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