Functional connectivity change across multiple cortical networks relates to episodic memory changes in aging.

@article{Fjell2015FunctionalCC,
  title={Functional connectivity change across multiple cortical networks relates to episodic memory changes in aging.},
  author={Anders M. Fjell and Markus H. Sneve and H{\aa}kon Grydeland and Andreas B Storsve and Ann-Marie Glas\o de Lange and Inge K. Amlien and Ole J\orgen R\ogeberg and Kristine B. Walhovd},
  journal={Neurobiology of aging},
  year={2015},
  volume={36 12},
  pages={3255-3268}
}
A major task of contemporary cognitive neuroscience of aging is to explain why episodic memory declines. Change in resting-state functional connectivity (rsFC) could be a mechanism accounting for reduced function. We addressed this through 3 studies. In study 1, 119 healthy participants (20-83 years) were followed for 3.5 years with verbal recall testing and magnetic resonance imaging. Independent of atrophy, recall change was related to change in rsFC in anatomically widespread areas. Striking… CONTINUE READING
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