Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival.

@article{Quaye2009FunctionalCS,
  title={Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival.},
  author={L. A. N. Quaye and Dimitra Dafou and Susan J Ramus and Honglin Song and Aleksandra Gentry-Maharaj and Maria Notaridou and Estrid V S Hogdall and Susanne Kr{\"u}ger Kjaer and Lise Christensen and Claus K. Hogdall and Douglas F. Easton and Ian J. Jacobs and Usha Menon and Paul P. D. Pharoah and Simon A. Gayther},
  journal={Human molecular genetics},
  year={2009},
  volume={18 10},
  pages={1869-78}
}
Common germline genetic variation and/or somatic alterations in tumours may be associated with survival in women diagnosed with ovarian cancer. The successful identification of genetic associations relies on a suitable strategy for identifying and testing candidate genes. We used microcell-mediated chromosome transfer approach and expression microarray analysis to identify genes that were associated with neoplastic suppression in ovarian cancer cell lines. Sixty-five tagging single nucleotide… CONTINUE READING