Functional complementation of dwf4 mutants of Arabidopsis by overexpression of CYP724A1.

@article{Zhang2012FunctionalCO,
  title={Functional complementation of dwf4 mutants of Arabidopsis by overexpression of CYP724A1.},
  author={Rujia Zhang and Xinjie Xia and Keith Lindsey and Pedro S C Ferreira da Rocha},
  journal={Journal of plant physiology},
  year={2012},
  volume={169 4},
  pages={421-8}
}
An essential step in the biosynthesis of bioactive brassinosteroids (BRs) in plants is the hydroxylation at C-22, a reaction catalyzed by P450 enzymes of the CYP90B and CYP724B subfamilies. Genes for both types of enzymes are present in many species, and in rice (Oryza sativa) and tomato (Solanum lycopersicum) both CYP90B and CYP724B enzymes contribute to C-22 hydroxylation. In Arabidopsis (Arabidopsis thaliana), C-22 hydroxylation of BRs is catalyzed by CYP90B1 (encoded by DWF4) and null dwf4… CONTINUE READING

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