Functional compensation for adipose differentiation-related protein (ADFP) by Tip47 in an ADFP null embryonic cell line.

@article{Sztalryd2006FunctionalCF,
  title={Functional compensation for adipose differentiation-related protein (ADFP) by Tip47 in an ADFP null embryonic cell line.},
  author={Carole Sztalryd and Ming Bell and Xinyue Lu and Pamela Mertz and Sabrina J Hickenbottom and Benny H-J Chang and Lawrence K Chan and Alan R. Kimmel and Constantine Londos},
  journal={The Journal of biological chemistry},
  year={2006},
  volume={281 45},
  pages={34341-8}
}
Ectopic accumulation of lipid droplets in non-adipose tissues correlates with the degree of insulin resistance in these tissues. Emerging evidence indicates that lipid droplets are specialized organelles that participate in lipid metabolism and intracellular trafficking. These properties are thought to derive from the lipid droplet-associated PAT protein family (perilipin, ADFP, and Tip47). The functions of the ubiquitously distributed adipose differentiation-related protein (ADFP) and Tip47… CONTINUE READING

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